User:Yummize/Toxicology testing
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[edit]The Origins of Toxicology
The study of poisons and toxic substances has a long history dating back to ancient times, when humans recognized the dangers posed by various natural compounds. However, the formalization and development of toxicology as a distinct scientific discipline can be attributed to notable figures like Paracelsus (1493–1541) and Orfila (1757–1853).
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Paracelsus (1493-1541): Often regarded as the "father of toxicology, Paracelsus, whose real name was Theophrastus von Hohenheim, challenged prevailing beliefs about poisons during the Renaissance era. He introduced the fundamental concept that "the dose makes the poison," emphasizing that the toxicity of a substance depends on its quantity. This principle remains a cornerstone of toxicology.
Mathieu Orfila (1787-1853): A Spanish-born chemist and toxicologist, Orfila made significant contributions to the field in the 19th century. He is best known for his pioneering work in forensic toxicology, particularly in developing methods for detecting and analyzing poisons in biological samples. Orfila's work played a vital role in establishing toxicology as a recognized scientific discipline and laid the groundwork for modern forensic toxicology practices in criminal investigations and legal cases.
References
[edit]7. ^ "Toxicology: Then and now" from Clinical Biochemistry, Volume 39, Issue 5, May 2006https://www.sciencedirect.com/science/article/pii/S0009912006000907?via%3Dihub
8. “History of Toxicology.” Toxicology Education Foundation, 2 Aug. 2023, toxedfoundation.org/history-of-toxicology/.
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