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From Wikipedia, the free encyclopedia

HYPHY (/ˈhaɪfaɪː/ HYE-fye) is a free multiplatform (Mac, Windows and UNIX) Computational phylogenetics software package intended to perform maximum likelihood analyses of genetic sequence data and equipped with tools to test various statistical hypotheses.[1] The HYPHY name is an abbreviation for "HYpothesis testing using PHYlogenies".[2]

HYPHY is developed by Sergei Kosakovsky Pond, Simon Frost, and Art Poon of UC San Diego, and Spencer Muse of North Carolina State University.

History

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The development of HyPhy started in 1997, with the first public release in 2000 and the most recent version as of Jan 2009 being 0.99+ beta, compiled on May 8, 2008.[2]

Software/code availability and license

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HYPHY is distributed as freeware with source code released under the GPL. Compiled binaries for Mac OS (9 and X) and Windows are available for download. There is also a source based distribution (under the GPL license), which can be used to build HyPhy on *nix systems.

A subset of HYPHY methods are also made available by the HYPHY team at UC San Diego in the form of the DataMonkey server

Notes

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  1. ^ Pond SL, Frost SD, Muse SV (2005). "HyPhy: hypothesis testing using phylogenies". Bioinformatics. 21 (5): 676–9. doi:10.1093/bioinformatics/bti079. PMID 15509596. {{cite journal}}: Unknown parameter |month= ignored (help)CS1 maint: multiple names: authors list (link)
  2. ^ a b "HYPHY page". Retrieved 2009-01-22.
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  • [1]: The HYPHY home page
  • [2]: The DataMonkey server, which supports a variety of HYPHY tools (at no cost).
  • [3]: HYPHY/DataMonkey support forums

[[Category:Computational phylogenetics]] [[Category:Bioinformatics software]]