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Protein-coding gene in the species Homo sapiens
Olfactory receptor 2K2 is a protein that in humans is encoded by the OR2K2 gene .[ 5] [ 6] [ 7]
Olfactory receptors interact with odorant molecules in the nose , to initiate a neuronal response that triggers the perception of a smell . The olfactory receptor proteins are members of a large family of G-protein-coupled receptors (GPCR) arising from single coding-exon genes. Olfactory receptors share a 7-transmembrane domain structure with many neurotransmitter and hormone receptors and are responsible for the recognition and G protein-mediated transduction of odorant signals. The olfactory receptor gene family is the largest in the genome. The nomenclature assigned to the olfactory receptor genes and proteins for this organism is independent of other organisms.[ 7]
^ a b c GRCh38: Ensembl release 89: ENSG00000171133 – Ensembl , May 2017^ a b c GRCm38: Ensembl release 89: ENSMUSG00000043385 – Ensembl , May 2017^ "Human PubMed Reference:" . National Center for Biotechnology Information, U.S. National Library of Medicine .^ "Mouse PubMed Reference:" . National Center for Biotechnology Information, U.S. National Library of Medicine .^ Parmentier M, Libert F, Schurmans S, Schiffmann S, Lefort A, Eggerickx D, Ledent C, Mollereau C, Gerard C, Perret J, et al. (Mar 1992). "Expression of members of the putative olfactory receptor gene family in mammalian germ cells". Nature . 355 (6359): 453– 5. Bibcode :1992Natur.355..453P . doi :10.1038/355453a0 . PMID 1370859 . S2CID 43926 . ^ Aloni R, Olender T, Lancet D (Jan 2007). "Ancient genomic architecture for mammalian olfactory receptor clusters" . Genome Biol . 7 (10): R88. doi :10.1186/gb-2006-7-10-r88 PMC 1794568 PMID 17010214 . ^ a b "Entrez Gene: OR2K2 olfactory receptor, family 2, subfamily K, member 2" .
Strausberg RL, Feingold EA, Grouse LH, et al. (2003). "Generation and initial analysis of more than 15,000 full-length human and mouse cDNA sequences" . Proc. Natl. Acad. Sci. U.S.A . 99 (26): 16899– 903. Bibcode :2002PNAS...9916899M . doi :10.1073/pnas.242603899 PMC 139241 PMID 12477932 . Malnic B, Godfrey PA, Buck LB (2004). "The human olfactory receptor gene family" . Proc. Natl. Acad. Sci. U.S.A . 101 (8): 2584– 9. Bibcode :2004PNAS..101.2584M . doi :10.1073/pnas.0307882100 PMC 356993 PMID 14983052 . Humphray SJ, Oliver K, Hunt AR, et al. (2004). "DNA sequence and analysis of human chromosome 9" . Nature . 429 (6990): 369– 74. Bibcode :2004Natur.429..369H . doi :10.1038/nature02465 . PMC 2734081 PMID 15164053 . Gerhard DS, Wagner L, Feingold EA, et al. (2004). "The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC)" . Genome Res . 14 (10B): 2121– 7. doi :10.1101/gr.2596504 . PMC 528928 PMID 15489334 .
This article incorporates text from the United States National Library of Medicine , which is in the public domain .
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