Endrin

Endrin
Names
	IUPAC name (1R,2S,3R,6S,7R,8S,9S,11R)-3,4,5,6,13,13-Hexachloro-10-oxapentacyclo[6.3.1.13,6.02,7.09,11]tridec-4-ene
	Other names Mendrin, Compound 269, (1aR,2S,2aS,3S,6R,6aR,7R,7aS)-3,4,5,6,9,9-hexachloro-1a,2,2a,3,6,6a,7,7a-octahydro-2,7:3,6-dimethanonaphtho[2,3-b]oxirene, 1,2,3,4,10,10-Hexachloro-6,7-epoxy-1,4,4a,5,6,7,8,8a-octahydro-1,4-endo,endo-5,8-dimethanonaphthalene
Identifiers
CAS Number	72-20-8 ;
3D model (JSmol)	Interactive image;
ChEBI	CHEBI:81526;
ChEMBL	ChEMBL44072;
ChemSpider	21782117 ;
ECHA InfoCard	100.000.705
EC Number	200-775-7;
KEGG	C18124 ;
PubChem CID	3048;
RTECS number	IO1575000;
UNII	OB9NVE7YCL ;
UN number	2761
CompTox Dashboard (EPA)	DTXSID6020561 ;
	SMILES C1C2C3C(C1C4C2O4)C5(C(=C(C3(C5(Cl)Cl)Cl)Cl)Cl)Cl;
Properties
Chemical formula	C12H8Cl6O
Molar mass	380.907 g/mol
Appearance	Colorless to tan crystalline solid
Density	1.77 g/cm3
Melting point	200 °C (392 °F; 473 K) (decomposes)
Solubility in water	0.23 mg/L
Vapor pressure	2.6 x 10-5 Pa
Hazards
	GHS labelling:
Pictograms	Template:GHS06Template:GHS08Template:GHS09
Signal word	Danger
Hazard statements	H301, H310, H351, H372, H410
Precautionary statements	P201, P202, P260, P262, P264, P270, P273, P280, P281, P301+P310, P302+P350, P308+P313, P310, P314, P321, P322, P330, P361, P363, P391, P405, P501
NFPA 704 (fire diamond)	2 0 0
Flash point	noncombustible
	Lethal dose or concentration (LD, LC):
LD50 (median dose)	3 mg/kg (oral, monkey); 16 mg/kg (oral, guinea pig); 10 mg/kg (oral, hamster); 3 mg/kg (oral, rat); 7 mg/kg (oral, rabbit); 1.4 mg/kg (oral, mouse)
LDLo (lowest published)	5 mg/kg (cat, oral)
	NIOSH (US health exposure limits):
PEL (Permissible)	TWA 0.1 mg/m3 [skin]
REL (Recommended)	TWA 0.1 mg/m3 [skin]
IDLH (Immediate danger)	2 mg/m3
	Except where otherwise noted, data are given for materials in their standard state (at 25 °C [77 °F], 100 kPa).
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	Infobox references

Endrin is an insecticide that was commonplace among cotton growers and for the treament of cereals. It was also used to kill rodents. It is a neurotoxin. It is a stereoisomer of Dieldrin. In the soil, it can take up to twelve years to decay. It is one of the twelve substances listed in the Stockholm Convention on Persistent Organic Pollutants, and its production, trade and use is banned since 2004.

References

1 2 "Endrin". Deutsche Gesellschaft für Technische Zusammenarbeit. Retrieved 13 March 2015.
↑ "Endrin (PDS)". IPCS. Archived from the original on 2 July 2014. Retrieved 13 March 2015.
1 2 3 4 NIOSH Pocket Guide to Chemical Hazards. "#0252". National Institute for Occupational Safety and Health (NIOSH).
1 2 "Endrin". Immediately Dangerous to Life or Health Concentrations (IDLH). National Institute for Occupational Safety and Health (NIOSH). 4 December 2014. Retrieved 19 March 2015.

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[CES-1] 1 2 "Endrin". Deutsche Gesellschaft für Technische Zusammenarbeit. Retrieved 13 March 2015.

[PDS-2] "Endrin (PDS)". IPCS. Archived from the original on 2 July 2014. Retrieved 13 March 2015.

[niosh-3] 1 2 3 4 NIOSH Pocket Guide to Chemical Hazards. "#0252". National Institute for Occupational Safety and Health (NIOSH).

[IDLH-4] 1 2 "Endrin". Immediately Dangerous to Life or Health Concentrations (IDLH). National Institute for Occupational Safety and Health (NIOSH). 4 December 2014. Retrieved 19 March 2015.

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