溴朵林

溴朵林
臨床資料
其他名稱	Bromadoline
ATC碼	未分配;
识别信息
	IUPAC命名法 4-bromo-N-[(1R,2R)-2-(dimethylamino)cyclohexyl]benzamide; ;
CAS号	67579-24-2
PubChem CID	6328449;
UNII	R8DWN01P1M;
CompTox Dashboard (EPA)	DTXSID40217897 ;
化学信息
化学式	C15H21BrN2O
摩尔质量	325.25 g·mol−1
3D模型（JSmol）	交互式图像;
	SMILES CN(C)[C@@H]1CCCC[C@H]1NC(=O)C2=CC=C(C=C2)Br;
	InChI InChI=1S/C15H21BrN2O/c1-18(2)14-6-4-3-5-13(14)17-15(19)11-7-9-12(16)10-8-11/h7-10,13-14H,3-6H2,1-2H3,(H,17,19)/t13-,14-/m1/s1; Key:UFDJFJYMMIZKLG-ZIAGYGMSSA-N;

溴朵林（U-47931E）^[1]是一种有机化合物，化学式为C₁₅H₂₁BrN₂O，它是Upjohn公司于1970年代研发^[2]的对μ-阿片受体具有选择性的類阿片镇痛药，^[3]其药效介于可待因和吗啡之间，略强于喷他佐辛。^[4]

参见

^ Unlisted Drugs 34–35. Chatham: Pharmaceutical Section, Special Libraries Association. 1982: 392. ISBN 978-0-913210-13-0.
^ Jacob Szmuszkovicz. Patent US4098904 - Analgesic N-(2-aminocycloaliphatic)benzamides. The Upjohn Company. 4 July 1978 [2023-09-22]. （原始内容存档于2016-10-26）.
^ Hayes AG, Skingle M, Tyers MB. Evaluation of the receptor selectivities of opioid drugs by investigating the block of their effect on urine output by beta-funaltrexamine. The Journal of Pharmacology and Experimental Therapeutics. March 1987, 240 (3): 984–8. PMID 3559988.
^ Hayes AG, Sheehan MJ, Tyers MB. Differential sensitivity of models of antinociception in the rat, mouse and guinea-pig to mu- and kappa-opioid receptor agonists. British Journal of Pharmacology. August 1987, 91 (4): 823–32. PMC 1853585 . PMID 2822190. doi:10.1111/j.1476-5381.1987.tb11281.x.