Pyruvate dehydrogenase complex: Revision history

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curprev 14:2914:29, 14 May 2025 2600:1702:1b20:36b0:7013:cb74:4774:2cb talk 31,811 bytes +2,307 Some details on insulin's role in this undo

curprev 02:0902:09, 16 February 2025 Djprasadian talk contribs 29,504 bytes −67 →Mechanism undo Tag: Visual edit

curprev 19:1219:12, 2 January 2025 Arthurfragoso talk contribs 29,571 bytes −33 dark mode fixes undo
curprev 06:0706:07, 2 January 2025 Arthurfragoso talk contribs 29,604 bytes −6 dark mode fix undo

curprev 03:0703:07, 13 December 2024 Synpath talk contribs 29,610 bytes +28 →Mechanism: upright and class change undo Tag: 2017 wikitext editor
curprev 02:5302:53, 13 December 2024 Synpath talk contribs 29,582 bytes +38 →Reaction: skin-invert-image filter for dark mode undo Tag: 2017 wikitext editor

curprev 20:0120:01, 15 August 2024 Moyogo talk contribs m 29,544 bytes −1 Greek alpha and beta undo

curprev 12:3512:35, 25 July 2024 Rudi Glockshuber talk contribs 29,545 bytes +158 oliomeric states of E1 and E3 descibed undo Tag: Visual edit
curprev 12:1612:16, 25 July 2024 Rudi Glockshuber talk contribs m 29,387 bytes +29 completion of nomenclature undo Tag: Visual edit
curprev 10:1510:15, 25 July 2024 Rudi Glockshuber talk contribs m 29,358 bytes +539 The changes refer to a more precise description of the species dependence of the subunit composition of PDCs. undo Tag: Visual edit

curprev 09:4609:46, 18 July 2024 Rudi Glockshuber talk contribs m 28,819 bytes +36 →more precise definition and description of the function of the periphealsubunit binding domain of the subunit E2 of the bacterial pyruvate dehydrogenase complex undo Tag: Visual edit

curprev 17:1817:18, 30 May 2024 Orenburg1 talk contribs m 28,783 bytes +1 sp undo

curprev 11:3811:38, 8 May 2024 Lukas Laysy talk contribs 28,782 bytes −4 Chemically speaking, a "hemithioacetal" is a completely different structural motif. undo Tag: Visual edit: Switched

curprev 11:4111:41, 17 April 2024 Rudi Glockshuber talk contribs m 28,786 bytes −71 NAD+ and CoA had been described as cofactors, but are indeed substrates becaused they are, in contrast to the cofactors FAD, TPP and lipoamide, turned over to reaction products when the PDC reaction cycle is completed. undo Tag: Visual edit

curprev 22:0022:00, 10 April 2024 Maxim Masiutin talk contribs 28,857 bytes +29 Added bibcode. | Use this tool. Report bugs. | #UCB_Gadget undo
curprev 16:3416:34, 10 April 2024 Rudi Glockshuber talk contribs 28,828 bytes +604 The changes correspond to the results of reference (9) (Meinhold et al, Sci Adv. 2024), in which the previously unknown dimerization of PSBD from E2 was described, as well as the selective binding of E1 homodimers to dimeric PSBD and the selective binding of E3 homodimers to monomeric PSBD. undo Tag: Visual edit

curprev 17:4817:48, 15 February 2024 Maxim Masiutin talk contribs 28,224 bytes +33 Fixed error to remove the page from Category:CS1 maint: PMC format. Added the cs1 style template to denote Vancouver ("vanc") citation style, because references contain "vauthors" attribute to specify the list of authors. Altered pmc. | Use this tool. Report bugs. | #UCB_Gadget undo
curprev 17:4217:42, 15 February 2024 Sarah-and-Sarah12 talk contribs 28,191 bytes +32 →Gram-negative bacteria: Included new findings on the architecture of gammaproteobacterial PDHc. The previous Ref (Izard et al., 1999, PNAS, 96, 4, pages 1240–1245) does not describe the subunit stoichiometry, but compares E2 arrangement in 24-mer (gram-negative) vs. 60-mer (gram-positive and eukaryotic), so it did not fit here. undo Tag: Visual edit: Switched
curprev 17:2417:24, 15 February 2024 Sarah-and-Sarah12 talk contribs 28,159 bytes +96 →Pyruvate dehydrogenase (E1): Included that E1 can be homodimer (e.g. in E. coli) or heterotetramer (e.g. in Human and Bacillus stearothermophilus). undo Tag: Visual edit

curprev 17:0517:05, 26 January 2024 DMacks talk contribs 28,063 bytes −12 →Mechanism: cleaner undo
curprev 15:3115:31, 26 January 2024 85.148.86.54 talk 28,075 bytes +20 →Mechanism: added more prevailing name of lipoate (as this is basically hiding the function of A-L-A as a cofactor) undo

curprev 12:5212:52, 25 January 2024 Neiltonks talk contribs 28,055 bytes −41 Changing short description from "Three-enzyme complex responsible for pyruvate decarboxylation" to "Three-enzyme complex" undo Tag: Shortdesc helper

curprev 19:2119:21, 7 December 2023 TypistMonkey talk contribs 28,030 bytes +284 Copyedit, linking, added cleanup tags and templates. undo Tag: Visual edit

curprev 15:3315:33, 22 November 2023 Randy Kryn talk contribs 27,746 bytes +2 →Evolutionary history: uppercase per proper name and Wikipedia style (Earth), paragraph break for wall of text undo

curprev 23:2323:23, 1 August 2023 DMacks talk contribs 27,744 bytes 0 →Reaction: better image undo

curprev 17:0717:07, 2 July 2023 Tom.Reding talk contribs m 27,744 bytes +2 →Dihydrolipoyl transacetylase (E2): Cleanup; WP:GenFixes on undo Tag: AWB

curprev 21:1221:12, 25 June 2023 Sammi Brie talk contribs 27,742 bytes +84 Adding local short description: "Three-enzyme complex responsible for pyruvate decarboxylation", overriding Wikidata description "Complex that carries out the oxidative decarboxylation of pyruvate to form acetyl-CoA; comprises subunits possessing three catalytic activities: pyruvate dehydrogenase (E1), dihydrolipoamide S-acetyltransferase (E2), and dihydrolipoamide dehydrogenas" undo Tag: Shortdesc helper

curprev 12:0712:07, 13 February 2023 Citation bot talk contribs 27,658 bytes −84 Removed proxy/dead URL that duplicated identifier. | Use this bot. Report bugs. | Suggested by Corvus florensis | #UCB_webform 827/3499 undo

curprev 02:4202:42, 29 January 2023 OAbot talk contribs m 27,742 bytes +16 Open access bot: doi added to citation with #oabot. undo

curprev 19:2819:28, 28 August 2022 Tom.Reding talk contribs m 27,726 bytes +7 + undo
curprev 19:2619:26, 28 August 2022 Tom.Reding talk contribs m 27,719 bytes +10 Ref cleanup; WP:GenFixes on undo Tag: AWB

curprev 08:0308:03, 20 July 2022 211.210.41.70 talk 27,709 bytes 0 →Dihydrolipoyl transacetylase (E2): change PBSD to PSBD undo Tag: Visual edit

curprev 04:4404:44, 22 June 2022 Citation bot talk contribs 27,709 bytes +38 Add: s2cid, pmid, pages. Removed parameters. Formatted dashes. | Use this bot. Report bugs. | Suggested by Abductive | #UCB_webform 501/1992 undo

curprev 11:4911:49, 11 April 2022 2601:246:4e00:c10:5cbd:e4b4:146b:9d48 talk 27,671 bytes +14 →Mechanism undo

curprev 23:3223:32, 20 March 2022 Pkbgenesproteins talk contribs m 27,657 bytes +5 →Localization of pyruvate decarboxylation: minor edit, added in the word "here" for clarity to my previous edit undo
curprev 23:3223:32, 20 March 2022 Pkbgenesproteins talk contribs 27,652 bytes +568 →Localization of pyruvate decarboxylation: I worded this carefully for now with "we may need further confirmation" just in case, and after looking into this some more, it does seem to be a form of secondary active transport. We should be more clear about what kind of "active" transport we mean here (primary versus secondary). The previous person did not specify if it was a primary or secondary active transport but was kind of vague and just said "consumed energy" ... undo

curprev 15:2715:27, 18 March 2022 Citation bot talk contribs 27,084 bytes +28 Add: pmc, pmid. | Use this bot. Report bugs. | Suggested by Headbomb | #UCB_toolbar undo
curprev 15:2615:26, 18 March 2022 Headbomb talk contribs 27,056 bytes +362 +a few undo

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