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Treponema succinifaciens

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Treponema succinifaciens
Scientific classification Edit this classification
Domain: Bacteria
Kingdom: Pseudomonadati
Phylum: Spirochaetota
Class: Spirochaetia
Order: Spirochaetales
Family: Treponemataceae
Genus: Treponema
Species:
T. succinifaciens
Binomial name
Treponema succinifaciens
Cwyk & Canale-Parola 1981

Treponema succinifaciens is a species of anaerobic spirochete bacteria first discovered in the intestines of swine in 1981.[1] The helical cells of T. succinifaciens grow to 16 μm in length and often form chains of cells when cultured.[2] T. succinifaciens is gram-negative and non spore-forming.[2]

In humans

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Treponema succinifaciens is found in the gut microbiome of many human populations, particularly those living traditional lifestyles. Although they have been found in humans living in urban areas, the occurrence is much rarer.[3][4][5] The rarer occurrence in urban populations is likely due to increased antibiotic use in urban populations

Genome

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The genome of T. succinifaciens is 2,897,425 base pairs in length. The bacterium contains 2,723 protein-coding as well as 63 RNA genes. It also contains 63 genes that are involved in motility.[2]

References

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  1. ^ Cwyk WM, Canale-Parola E (September 1979). "Treponema succinifaciens sp. nov., an anaerobic spirochete from the swine intestine". Archives of Microbiology. 122 (3): 231–9. Bibcode:1979ArMic.122..231C. doi:10.1007/bf00411285. PMID 120726.
  2. ^ a b c Han C, Gronow S, Teshima H, Lapidus A, Nolan M, Lucas S, et al. (July 2011). "Complete genome sequence of Treponema succinifaciens type strain (6091)". Standards in Genomic Sciences. 4 (3): 361–70. doi:10.4056/sigs.1984594. PMC 3156407. PMID 21886863.
  3. ^ Mancabelli L, et al. (2017). "Meta-analysis of the human gut microbiome from urbanized and pre-agricultural populations". Environ Microbiol. 19: 1379–1390. doi:10.1111/1462-2920.13692.
  4. ^ Tamburini FB, Maghini D, Oduaran OH, et al. (2022). "Short- and long-read metagenomics of urban and rural South African gut microbiomes reveal a transitional composition and undescribed taxa". Nature Communications. 13 (1): 926. Bibcode:2022NatCo..13..926T. doi:10.1038/s41467-021-27917-x. PMC 8863827. PMID 35194028.
  5. ^ Maghini DG, et al. (2025). "Expanding the human gut microbiome atlas of Africa". Nature. 638: 718–728. doi:10.1038/s41586-024-08485-8.