Edit filter log

'The '''Anatomical Therapeutic Chemical (ATC) Classification System''' is used for the [[drug class|classification]] of [[Medication|active ingredient]]s of [[drug]]s according to the [[organ (anatomy)|organ]] or [[system]] on which they act and their [[therapeutic]], [[pharmacological]] and chemical properties. It is controlled by the [[World Health Organization]] Collaborating Centre for Drug Statistics Methodology (WHOCC), and was first published in 1976.<ref>{{cite web|url=http://www.whocc.no/atc_ddd_methodology/history/|publisher=WHO Collaborating Centre for Drug Statistics Methodology|title=ATC/DDD Methodology: History}}</ref> This [[Pharmaceutical code|pharmaceutical coding system]] divides drugs into different groups according to the organ or system on which they act and/or their [[medicine|therapeutic]] and [[chemical classification|chemical characteristics]]. Each bottom-level ATC code stands for a pharmaceutically used substance, or a combination of substances, in a single indication (or use). This means that one drug can have more than one code: [[acetylsalicylic acid]] (aspirin), for example, has {{ATC|A01|AD05}} as a drug for local [[mouth|oral]] treatment, {{ATC|B01|AC06}} as a [[platelet inhibitor]], and {{ATC|N02|BA01}} as an [[analgesic]] and [[antipyretic]]. On the other hand, several different brands share the same code if they have the same active substance and indications. == Classification == In this system, drugs are classified into groups at 5 different levels:<ref>{{cite web|url=http://www.whocc.no/atc/structure_and_principles/|publisher=WHO Collaborating Centre for Drug Statistics Methodology|title=ATC: Structure and principles}}</ref> === First level === The first level of the code indicates the anatomical main group and consists of one letter. There are 14 main groups:<ref>{{cite web|url=http://www.whocc.no/atc_ddd_index/|publisher=WHO Collaborating Centre for Drug Statistics Methodology|title=ATC/DDD Index}}</ref> {| class="wikitable" |- !Code !Contents |- style="background:#fd6" | '''[[ATC code A|A]]''' | [[Alimentary tract]] and [[metabolism]] |- style="background:MistyRose" | '''[[ATC code B|B]]''' | [[Blood]] and [[haematopoiesis|blood forming organs]] |- style="background:MistyRose" | '''[[ATC code C|C]]''' | [[Cardiovascular system]] |- style="background:Linen" | '''[[ATC code D|D]]''' | [[Dermatological]]s |- style="background:#beb" | '''[[ATC code G|G]]''' | [[Genito-urinary system]] and [[sex hormone]]s |- style="background:#efefef" | '''[[ATC code H|H]]''' | Systemic [[hormonal]] preparations, excluding sex hormones and insulins |- style="background:PowderBlue" | '''[[ATC code J|J]]''' | [[Antiinfective]]s for systemic use |- style="background:Plum" | '''[[ATC code L|L]]''' | [[Antineoplastic]] and [[immunomodulator|immunomodulating]] agents |- style="background:Linen" | '''[[ATC code M|M]]''' | [[Musculo-skeletal system]] |- style="background:LightYellow" | '''[[ATC code N|N]]''' | [[Nervous system]] |- style="background:PowderBlue" | '''[[ATC code P|P]]''' | [[Antiparasitic]] products, [[insecticide]]s and [[insect repellent|repellent]]s |- style="background:MistyRose" | '''[[ATC code R|R]]''' | [[Respiratory system]] |- style="background:LightYellow" | '''[[ATC code S|S]]''' | [[Sensory organ]]s |- style="background:#ccf" | '''[[ATC code V|V]]''' | Various |} ''Example'': [[ATC code C|'''C''']] [[Cardiovascular system]] === Second level === The second level of the code indicates the therapeutic main group and consists of two digits. ''Example'': [[ATC code C03|C'''03''']] [[Diuretic]]s === Third level === The third level of the code indicates the therapeutic/pharmacological subgroup and consists of one letter. ''Example'': C03'''C''' High-ceiling diuretics === Fourth level === The fourth level of the code indicates the chemical/therapeutic/pharmacological subgroup and consists of one letter. ''Example'': C03C'''A''' [[Sulfonamide (medicine)|Sulfonamide]]s === Fifth level === The fifth level of the code indicates the chemical substance and consists of two digits. ''Example'': C03CA'''01''' [[Furosemide]] === ATCvet === The ''Anatomical Therapeutic Chemical Classification System for veterinary medicinal products'' (ATCvet) is used to classify [[veterinary]] drugs. ATCvet codes can be created by placing the letter Q in front of the ATC code of most human medications. For example, furosemide for veterinary use has the code '''Q'''C03CA01. Some codes are used exclusively for veterinary drugs, such as ''[[ATCvet code QI|QI]] Immunologicals'', ''[[ATCvet code QJ51|QJ51]] Antibacterials for intramammary use'' or ''QN05AX90 [[amperozide]]''.<ref>{{cite web|url=http://www.whocc.no/atcvet/atcvet/|publisher=WHO Collaborating Centre for Drug Statistics Methodology|title=ATCvet|accessdate=2015-02-15}}</ref> == Defined daily dose == {{main|Defined daily dose}} The ATC system also includes defined daily doses (DDDs) for many drugs. This is a measurement of drug consumption based on the usual daily dose for a given drug. According to the definition, "[t]he DDD is the assumed average maintenance dose per day for a drug used for its main indication in adults."<ref>{{cite web|url=http://www.whocc.no/ddd/definition_and_general_considera/|publisher=WHO Collaborating Centre for Drug Statistics Methodology|title=DDD: Definition and general considerations}}</ref> == Purpose == {{empty section|date=April 2014}} ==National adaptations== National issues of the ATC classification, such as the [[Germany|German]] ''Anatomisch-therapeutisch-chemische Klassifikation mit Tagesdosen'', may include additional codes and DDDs not present in the WHO version.<ref>{{cite web|url=http://www.dimdi.de/static/de/klassi/atcddd/atc-gesetze.htm|publisher=Deutsches Institut für Medizinische Dokumentation und Information|title=ATC-Klassifikation mit DDD: Gesetzlicher Hintergrund|language=German}}</ref> ==Updates to ATC== ATC follows guidelines <ref>{{cite web|title=Guidelines for ATC classification and DDD assignment|date=2014-12-16|publisher=WHO Collaborating Centre for Drug Statistics Methodology|url=http://www.whocc.no/atc_ddd_publications/guidelines/}}</ref> in creating new codes for newly approved drugs. In order to create a new ATC code, an application has to be sent to ATC. New ATC codes are published twice annually.<ref>{{cite web|title=New ATC|date=2015-04-29|publisher=WHO Collaborating Centre for Drug Statistics Methodology|url=http://www.whocc.no/atc/lists_of_new_atc_ddds_and_altera/new_atc/}}</ref> A formal release of new ATC edition occurs once a year. == See also == * [[Classification of Pharmaco-Therapeutic Referrals]] (CPR) * [[Family medicine]] / [[Family practice]] * [[General practice]] * [[ICD-10]] International Classification of Diseases * [[International Classification of Primary Care]] (ICPC-2) / [[ICPC-2 PLUS]] *[[Medical classification]] * [[Pharmaceutical care]] * [[Pharmacist]] / [[Pharmacy]] * [[Pharmacotherapy]] * [[Primary care]] * [[Referral (medicine)]] * [[RxNorm]] == References == {{Research help|Med}} {{Reflist}} == External links == * {{cite web|url=http://www.whocc.no/|title= WHOCC Homepage|publisher=WHO Collaborating Centre for Drug Statistics Methodology}} * {{cite web|url=http://sydney.edu.au/medicine/fmrc/atc/|title=ATC: Introduction|publisher=Family Medicine Research Centre, [[University of Sydney]]}} * [http://www.ephmra.org/Classification EphMRA Anatomical Classification (ATC and NFC)] * [http://www.atccode.com ATC Code List] {{Major Drug Groups}} {{Medical classification}} [[Category:Drugs]] [[Category:ATC codes| ]] [[Category:Drugs by target organ system| ]] [[Category:Pharmacological classification systems]]'