Escherichia coli O104:H4
Escherichia coli O104:H4 is a rare enterohemorrhagic strain of the bacterium Escherichia coli, and the cause of the 2011 Escherichia coli O104:H4 outbreak.Vorlage:Citation needed The "O" in the serological classification identifies the cell wall lipopolysaccharide antigen, and the "H" identifies the flagella antigen.
Genomic sequencing by BGI Shenzhen revealed that the bacteria belong to a "new super-toxic strain", a hybrid that has acquired some virulence abilities of enteroaggregative E. coli (EAEC) strains by horizontal gene transfer.[1][2]
Prior to the 2011 outbreak, only one case had been documented in literature, and this case was a woman in Korea in 2005.[3] A presumably related strain, O104:H21, caused an outbreak of hemorrhagic colitis in Montana in 1994.
References
Vorlage:Gram-negative bacterial diseases Vorlage:Consumer Food Safety
- ↑ BGI Sequences Genome of the Deadly E. Coli in Germany and Reveals New Super-Toxic Strain. BGI, 2. Juni 2011, abgerufen am 2. Juni 2011.
- ↑ David Tribe: BGI Sequencing news: German EHEC strain is a chimera created by horizontal gene transfer. 2. Juni 2011, abgerufen am 2. Juni 2011.
- ↑ Vorlage:Vcite journal