TCPy
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| Names | |
|---|---|
| Preferred IUPAC name
3,5,6-Trichloropyridin-2(1H)-one | |
| Identifiers | |
3D model (JSmol)
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| ChemSpider | |
| ECHA InfoCard | 100.026.733 |
PubChem CID
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| UNII | |
CompTox Dashboard (EPA)
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| Properties | |
| C5H2Cl3NO | |
| Molar mass | 198.43 g·mol−1 |
| Density | 1.67g/cm3 |
| Melting point | 172 to 174 °C (342 to 345 °F; 445 to 447 K) |
| Boiling point | 254.8 °C (490.6 °F; 528.0 K) at 760 mmHg |
| Hazards | |
| Flash point | 107.9 °C (226.2 °F; 381.0 K) |
Except where otherwise noted, data are given for materials in their standard state (at 25 °C [77 °F], 100 kPa).
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TCPy or 3,5,6-trichloro-2-pyridinol is a cyclic hydrocarbon, specifically a chlorinated version of 2-pyridone.
Pesticides can be a precursor to TCPy. TCPy is a metabolite of the herbicide triclopyr,[1] and of the insecticides chlorpyrifos and chlorpyrifos-methyl. A study in Massachusetts reported a correlation between exposure to TCPy and lower testosterone levels in men.[2] According to this source, exposure is "widespread" and of "potential public health importance".
References
- ^ "Draft Vegetation Management: Triclopyr" (PDF). San Francisco Forest Alliance. Marin Municipal Water District. 2008. Retrieved 12 April 2021.
- ^ Meeker, J. D.; Ryan, L.; Barr, D. B.; Hauser, R. (2006). "Exposure to Nonpersistent Insecticides and Male Reproductive Hormones". Epidemiology. 17 (1): 61–68. doi:10.1097/01.ede.0000190602.14691.70. PMID 16357596.