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Hepatitis C virus stem-loop VII

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Hepatitis C virus stem-loop VII
Predicted secondary structure and sequence conservation of HCV_SLVII
Identifiers
SymbolHCV_SLVII
RfamRF00468
Other data
RNA typeCis-reg
Domain(s)Viruses
SOSO:0000233
PDB structuresPDBe

Hepatitis C virus stem-loop VII is a regulatory element found in the coding region of the RNA-dependent RNA polymerase gene, NS5B. Similarly to stem-loop IV, the stem-loop structure is important (but not essential) for colony formation, though its exact function and mechanism are unknown.[1]

See also

References

  1. ^ Lee H, Shin H, Wimmer E, Paul AV (October 2004). "cis-acting RNA signals in the NS5B C-terminal coding sequence of the hepatitis C virus genome". Journal of Virology. 78 (20): 10865–10877. doi:10.1128/JVI.78.20.10865-10877.2004. PMC 521798. PMID 15452207.