Methylation specific oligonucleotide microarray
Methylation specific oligonucleotide microarray, also known as MSO microarray, was developed as a technique to map epigenetic methylation changes in DNA of cancer cells.[1]
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Methylation specific oligonucleotide microarray was developed as a technique to map methylation changes in DNA in cancer. This technique was developed by Professor Tim Hui-Ming Huang and was published in journal Genome Research on 2002 (Gitan et al., 2002). The method utilizes bisulfite-modified DNA that is used as templates for PCR amplification, which is subsequently hybridized to oligonucleotide microarray.
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- Resources, information and specific protocols for DNA Methylation Analysis
- Software for DNA Methylation Analysis
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- ^ Gitan, Raad S.; Shi, Huidong; Chen, Chuan-Mu; Yan, Pearlly S.; Huang, Tim Hui-Ming (2002). "Methylation-Specific Oligonucleotide Microarray: A New Potential for High-Throughput Methylation Analysis". Genome Research. 12 (1): 158–164. doi:10.1101/gr.202801. ISSN 1088-9051. PMID 11779841.