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Craig plot

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The Craig plot, named after Paul N. Craig, is a plot of two substituent parameters (e.g. Hansch-Fujita π constant and sigma constant) used in rational drug design.[1]

Craig plot showing values of Hansch pi and Hammett sigma constants for 26 common organic substituents
Craig plot showing values of Hansch pi and Hammett sigma constants for 26 common organic substituents

Two most used forms of a Craig plot are

See also

References

  1. ^ "IUPAC glossary". Archived from the original on 2006-12-09. Retrieved 2006-12-14.

1. P.N. Craig, J.Med.Chem., 14, 680-684 (1971).[1]


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  1. ^ Craig, Paul N. "Interdependence between physical parameters and selection of substituent groups for correlation studies". Journal of Medicinal Chemistry. 14: 680–684. doi:10.1021/jm00290a004.
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