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Replication timing quantitative trait loci

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A replication timing quantitative trait loci (or rtQTL) is a genetic variation producing a differential use of replication origins, exhibiting allele-specific effects on replication timing.[1] Originally, 16 rtQTL were found in an analysis of human genomes.

References

  1. ^ Koren, Amnon; Polak Paz; Nemesh James; Michaelson Jacob J; Sebat Jonathan; Sunyaev Shamil R; McCarroll Steven A (Dec 2012). "Differential relationship of DNA replication timing to different forms of human mutation and variation". Am. J. Hum. Genet. 91 (6). United States: 1033–40. doi:10.1016/j.ajhg.2012.10.018. PMC 3516607. PMID 23176822.


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