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Barettin is a bromine alkaloid made of a dehydrogenated bromine derivative of tryptophan linked by two peptide bonds to an arginine residue forming a 2,5-diketopiperazine nucleus. It is a cyclic dipeptide.

It is found in the deep-water sponge Geodia barretti.

Category:Indole alkaloids Category:Bromoarenes Category:Guanidines Category:Lactams Category:Piperazines Category:Alkenes Category:Peptides