Signal recognition particle 9

SRP9
Available structures
PDB	Ortholog search: PDBe RCSB
List of PDB id codes
	1E8O, 1E8S, 1RY1, 4UYJ, 4UYK, 5AOX
Identifiers
Aliases	SRP9, ALURBP, signal recognition particle 9kDa, signal recognition particle 9
External IDs	OMIM: 600707; MGI: 1350930; HomoloGene: 37737; GeneCards: SRP9; OMA:SRP9 - orthologs
Gene location (Human)
Chr.	Chromosome 1 (human)
End	225,790,468 bp
Gene location (Mouse)
Chr.	Chromosome 1 (mouse)
End	181,959,972 bp
RNA expression pattern
	Top expressed in
	ganglionic eminence; ; ventricular zone; ; endometrium; ; islet of Langerhans; ; corpus callosum; ; Hypothalamus; ; Achilles tendon; ; rectum; ; substantia nigra; ; C1 segment;
	Top expressed in
	supraoptic nucleus; ; facial motor nucleus; ; primitive streak; ; vestibular sensory epithelium; ; barrel cortex; ; Epithelium of choroid plexus; ; morula; ; neural tube; ; right kidney; ; cumulus cell;
	More reference expression data
	n/a
Gene ontology
Molecular function	signal recognition particle binding; 7S RNA binding; protein binding; RNA binding;
Cellular component	cytoplasm; signal recognition particle receptor complex; signal recognition particle; cytosol; signal recognition particle, endoplasmic reticulum targeting;
Biological process	negative regulation of translational elongation; SRP-dependent cotranslational protein targeting to membrane; SRP-dependent cotranslational protein targeting to membrane, translocation;
	Sources:Amigo / QuickGO
Orthologs
	6726
	27058
	ENSG00000143742
	ENSMUSG00000026511
	P49458
	P49962
	NM_003133; NM_001130440
	NM_012058
	NP_001123912; NP_003124; NP_001123912.1
	NP_036188
	Wikidata
View/Edit Human	View/Edit Mouse

Signal recognition particle 9 is a protein that in humans is encoded by the SRP9 gene. ^[5]

References

^ ^a ^b ^c GRCh38: Ensembl release 89: ENSG00000143742 – Ensembl, May 2017
^ ^a ^b ^c GRCm38: Ensembl release 89: ENSMUSG00000026511 – Ensembl, May 2017
^ "Human PubMed Reference:". National Center for Biotechnology Information, U.S. National Library of Medicine.
^ "Mouse PubMed Reference:". National Center for Biotechnology Information, U.S. National Library of Medicine.
^ "Entrez Gene: Signal recognition particle 9". Retrieved 2018-04-10.

Rho JH, Qin S, Wang JY, Roehrl MH (July 2008). "Proteomic expression analysis of surgical human colorectal cancer tissues: up-regulation of PSB7, PRDX1, and SRP9 and hypoxic adaptation in cancer". J. Proteome Res. 7 (7): 2959–72. doi:10.1021/pr8000892. PMC 2693877. PMID 18549262.
Mary C, Scherrer A, Huck L, Lakkaraju AK, Thomas Y, Johnson AE, Strub K (May 2010). "Residues in SRP9/14 essential for elongation arrest activity of the signal recognition particle define a positively charged functional domain on one side of the protein". RNA. 16 (5): 969–79. doi:10.1261/rna.2040410. PMC 2856890. PMID 20348448.

This article on a gene on human chromosome 1 is a stub. You can help Wikipedia by expanding it.

[refGRCh38Ensembl-1] GRCh38: Ensembl release 89: ENSG00000143742 – Ensembl, May 2017

[refGRCm38Ensembl-2] GRCm38: Ensembl release 89: ENSMUSG00000026511 – Ensembl, May 2017

[3] "Human PubMed Reference:". National Center for Biotechnology Information, U.S. National Library of Medicine.

[4] "Mouse PubMed Reference:". National Center for Biotechnology Information, U.S. National Library of Medicine.

[entrez-5] "Entrez Gene: Signal recognition particle 9". Retrieved 2018-04-10.

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References

Further reading