Carr index
The Carr index (also: Carr's index[1] or Carr's Compressibility Index[2]) is an indication of the compressibility of a powder. It is named after the scientist Ralph J. Carr, Jr.
The Carr index is calculated by the formula <math>C
The Carr index is frequently used in pharmaceutics as an indication of the flowability of a powder. In a free-flowing powder, the bulk density and tapped density would be close in value, therefore, the Carr index would be small. On the other hand, in a poor-flowing powder where there are greater interparticle interactions, the difference between the bulk and tapped density observed would be greater, therefore, the Carr index would be larger.[3] A Carr index greater than 25 is considered to be an indication of poor flowability, and below 15, of good flowability.<ref>{{cite book |author1=Kanig, Joseph L. |author2=Lachman, Leon |author3=Lieberman, Herbert A. |title=The Theory and Pra
- ^ Bowker, Michael I. & P. Heinrich Stahl. 2008. "Preparation of Water-Soluble Compounds through Salt Formation." In Camille Georges Wermuth, ed. The Practice of Medical Chemistry, pp. 747–766. Burlington, MA: Elsevier, p. 756.
- ^ Podczeck, Fridun & Brian E. Jones, eds. 2007. Pharmaceutical Capsules'111.
- ^ http://www.pharmacopeia.cn/v29240/usp29nf24s0_c616.html
General Bibliography
Mark Gibson (2001). Pharmaceutical Preformulation and Formulation: A Practical Guide from Candidate Drug Selection to Commercial Dosage Form. Boca Raton: CRC Press. ISBN 1-57491-120-1.
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