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Random chimeragenesis on transient templates

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RACHITT (random chimeragenesis on transient templates) is a method to perform molecular mutagenesis at a high recombination rate. DNA shuffling is a similar but less powerful method used in directed evolution experiments.

Reference

  • Coco, W.M. et al. Nat. Biotechnol. 19, 354–359 (2001).
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