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Substrate analog

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Substrate analogs (substrate state analogues), are chemical compounds with a chemical structure that resemble the substrate molecule in an enzyme-catalyzed chemical reaction. Substrate analogs can act as competitive inhibitors of an enzymatic reaction. An example is phosphoramidate to the Tetrahymena group I ribozyme[1]

See also

References

  1. ^ Hanna, Raven L.; Gryaznov, Sergei M.; Doudna, Jennifer A. (2000-11-01). "A phosphoramidate substrate analog is a competitive inhibitor of the Tetrahymena group I ribozyme". Chemistry & Biology. 7 (11): 845–854. doi:10.1016/S1074-5521(00)00033-8. ISSN 1074-5521. PMID 11094338.


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