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Hepatitis E virus cis-reactive element

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Hepatitis E virus cis-reactive element
Predicted secondary structure and sequence conservation of HepE_CRE
Identifiers
SymbolHepE_CRE
RfamRF00550
Other data
RNA type Cis-reg
Domain(s)Viruses
SOSO:0000233
PDB structuresPDBe

The hepatitis E virus cis-reactive element is a RNA element that is thought to be essential for "some step in gene expression".[1] The mutation of this element resulted in hepatitis E strains which were unable to infect rhesus macaques (Macaca mulatta).[1]

References

  1. ^ a b Graff, J; Nguyen H; Yu C; Elkins WR; St Claire M; Purcell RH; Emerson SU (2005). "The open reading frame 3 gene of hepatitis E virus contains a cis-reactive element and encodes a protein required for infection of macaques". J Virol. 79 (11): 6680–6689. doi:10.1128/JVI.79.11.6680-6689.2005. PMC 1112134. PMID 15890906.
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