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Drug vectorization

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In pharmacology and medicine vectorization of drugs refers to (intracellular) targeting with plastic or silicon nanoparticles or liposomes to which pharmacologically active substances are reversibly bound or attached by adsorption.[1][2]

CNRS researchers have devised a way to overcome the problem of multidrug resistance using polyalkylcyanoacrylate (PACA) nanoparticles as "vectors".[3]

References

  1. ^ Couvreur P. (2001). "Drug vectorization or how to modulate tissular and cellular distribution of biologically active compounds". Ann Pharm Fr. 59 (4): 232–8. PMID 11468577.
  2. ^ "Antibody-functionalized porous silicon nanoparticles for vectorization of hydrophobic drugs". Adv Healthc Mater. 2 (5): 718–27. 2013. doi:10.1002/adhm.201200335. PMID 23203914.
  3. ^ http://www.cnrs.fr/Cnrspresse/en380a6.htm

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