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Reliability theory of aging and longevity

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Reliability theory of aging and longevity


References

  • Gavrilov LA, Gavrilova NS. Reliability Theory of Aging and Longevity. In: Masoro E.J. & Austad S.N.. (eds.): Handbook of the Biology of Aging, Sixth Edition. Academic Press. San Diego, CA, USA, 2006, 3-42. ISBN 0-12-088387-2
  • Gavrilov LA, Gavrilova NS. Models of Systems Failure in Aging. In: P Michael Conn (Editor): Handbook of Models for Human Aging, Burlington, MA : Elsevier Academic Press, 2006. 45-68. ISBN 0-12-369391-8.
  • Gavrilov LA, Gavrilova NS. Why We Fall Apart. Engineering's Reliability Theory Explains Human Aging. IEEE Spectrum, 2004, 41(9): 30-35.
  • Gavrilov LA, Gavrilova NS. The Reliability-Engineering Approach to the Problem of Biological Aging. Annals of the New York Academy of Sciences, 2004, 1019: 509-512. PMID 15247076
  • Gavrilov L.A., Gavrilova N.S. The quest for a general theory of aging and longevity. Science's SAGE KE (Science of Aging Knowledge Environment) for 16 July 2003; Vol. 2003, No. 28, 1-10. http://sageke.sciencemag.org, PMID 12867663
  • Gavrilov L.A., Gavrilova N.S. The reliability theory of aging and longevity. Journal of Theoretical Biology, 2001, 213(4): 527-545. doi:10.1006/jtbi.2001.2430 PMID 11742523
  • Abernethy, John. Gompertzian mortality originates in the winding-down of the mitotic clock. Journal of Theoretical Biology, 1998, 192, 419-435.
  • Leonid A. Gavrilov & Natalia S. Gavrilova (1991), The Biology of Life Span: A Quantitative Approach. New York: Harwood Academic Publisher, ISBN 3-7186-4983-7
  • Gavrilov, L.A. A mathematical model of the aging of animals. Proc. Acad. Sci. USSR [Doklady Akademii Nauk SSSR], 1978, 238(2): 490-492. English translation by Plenum Publ Corp: pp.53-55. PMID 624242
  • Abernethy JD. The exponential increase in mortality rate with age attributed to wearing-out of biological components. Journal of Theoretical Biology, 1979, 80, 333-354.
  • Gavrilov, L.A., Gavrilova, N.S., Yaguzhinsky, L.S. The main regularities of animal aging and death viewed in terms of reliability theory. J. General Biology [Zhurnal Obschey Biologii], 1978, 39(5): 734-742. PMID 716614
  • Witten, T.M., Investigating the aging mammalian system: Cellular levels and beyond, Proc. 25th Annual Meeting of the Society for General Systems Research, (1981) 309-315.
  • Witten, T.M., A return to time, cells, systems, and aging: I. Rethinking the concepts of senescence in mammalian systems, Mech. Aging and Dev., 21(1983)69-81.
  • Witten, T.M., A return to time, cells, systems, and aging: II. Relational and reliability theoretic aspects of senescence in mammalian systems, Mech. Aging and Dev., 27 (1984) 323-340.
  • Witten, T.M., Reliability theoretic methods and aging: Critical elements, hierarchies, and longevity---Interpreting survival curves, (in) The Molecular Biology of Aging (eds.) A. Woodhead, A. Blackett, and R. Setlow (Plenum Press, N.Y. 1985).
  • Witten, T.M., A return to time, cells, systems and aging: III. Critical elements, hierarchies, and Gompertzian dynamics, Mech. Ageing and Dev., 32 (1985) 141-177.
  • Witten, T.M., A return to time, cells, system, and aging: IV. Further thoughts on Gompertzian survival dynamics---The neonatal years, Mech. Aging and Dev., 33 (1985) 177-190.
  • Witten, T.M., Information content of biological survival curves arising in aging experiments: Some further thoughts, (in) Evolution of Aging Processes in Animals (ed.) A. Woodhead and K.H. Thompson (Plenum Press, N.Y., 1987).
  • Witten, T.M., A return to time, cells, systems, and aging: V. Further thoughts on Gompertzian survival dynamics --- the geriatric years, Mech. Aging and Dev., 46(1988) 175-200.

Media coverage

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