Talk:Mevalonate pathway

Medicine Start‑class Low‑importance

	Medicine portal This article is within the scope of WikiProject Medicine, which recommends that medicine-related articles follow the Manual of Style for medicine-related articles and that biomedical information in any article use high-quality medical sources. Please visit the project page for details or ask questions at Wikipedia talk:WikiProject Medicine.MedicineWikipedia:WikiProject MedicineTemplate:WikiProject Medicinemedicine
Start	This article has been rated as Start-class on Wikipedia's content assessment scale.
Low	This article has been rated as Low-importance on the project's importance scale.

Rename article to mevalonate pathway

The mevalonate pathway is more commonly used and accepted than HMG-CoA reductase pathway. So, I think, the mevalonate kinase a better one as the article title.

In any case having abbreviations in the title is not proper either. One way or another, this article should be retitled. I don't know the topic well enough to know what's best, so maybe others can make suggestions. Edgar181 12:49, 22 February 2006 (UTC)[reply]

You are right. I will do it. The pathway also ends with production of prenyl-diphosphate --Kupirijo 03:06, 5 December 2006 (UTC)[reply]

Page moved. Cheers. -GTBacchus^(talk) 04:36, 10 December 2006 (UTC)[reply]

structure of 3-hydroxy-3-methylglutaryl CoA

I believe you have to many carbons in 3-hydroxy-3-methylglutaryl CoA, the carbon attached to the carbonyl at position 5 needs to be a OH/O- group.

I agree, and have left User:Jag123 a message requesting the fix. --David Iberri (talk) 14:56, 3 August 2006 (UTC)[reply]

Is anybody going to fix it? Do we have a repository of chemical structures in svg format? It would be nice if we had a database of ChemDraw structures. Does anybody know?--Kupirijo 15:59, 11 October 2006 (UTC)[reply]

Refs

Uclasci1616‎ added some content followed by a number of references, but there is no referencing to them. I've moved them here for... well... reference.

Holstein, S. A., and Hohl, R. J. (2004) Isoprenoids: Remarkable Diversity of Form and Function. Lipids 39, 293−309

Miziorko H (2011) Enzymes of the mevalonate pathway of isoprenoid biosynthesis. Arch Biochem Biophys 505:131-143.

Goldstein, J. L., and Brown, S. B. (1990) Regulation of the mevalonate pathway. Nature 343, 425−430

Buhaescu I, Izzedine H (2007) Mevalonate pathway: areview of clinical and therapeutical implications. ClinBiochem 40:575–584.

Dellas, N., Thomas, S. T., Manning, G., and Noel, J. P. (2013) Discovery of a metabolic alternative to the classical mevalonate pathway. eLife 2, e00672

Vinokur JM, Korman TP, Cao Z, Bowie JU (2014) Evidence of a novel mevalonate pathway in archaea. Biochemistry 53:4161–4168.

Azami Y, Hattori A, Nishimura H, Kawaide H, YoshimuraT, Hemmi H (2014) (R)-mevalonate-3-phosphate is an intermediate of the mevalonate pathway in Thermoplasma acidophilum. J Biol Chem 289:15957–15967.

"Lipitor becomes world's top-selling drug". Crain's New York Business. 2011-12-28.

JFW | T@lk 09:27, 29 July 2015 (UTC)[reply]