Craig plot
The Craig plot (named after Paul N. Craig)Cite error: There are <ref> tags on this page without content in them (see the help page). is a plot of two substituent parameters (e.g. Hansch-Fujita π constant and sigma constant) used in rational drug design.[1]
Two most used forms of a Craig plot are
- plotting the sigma constants of the Hammett equation versus hydrophobicity
- plotting the steric terms of the Taft equation against hydrophobicity
See also
References
1. P.N. Craig, J.Med.Chem.,14, 661 (1971).
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