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Hierarchical editing language for macromolecules

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The Hierarchical Editing Language for Macromolecules (HELM) is a method of describing complex biological molecules. It is a notation that is machine readable to render the composition and structure of peptides, proteins, oligonucleotides, and related small molecule linkers.[1]

HELM was developed by a consortium of pharmaceutical companies in what is known as the Pistoia Alliance. Development began in 2008. In 2012 the notation was published openly and for free.[2]

The HELM open source project can be found on Github.


See also

References

  1. ^ Zhang, Tianhong; Li, Hongli; Xi, Hualin; Stanton, Robert V.; Rotstein, Sergio H. (2012). "HELM: A Hierarchical Notation Language for Complex Biomolecule Structure Representation". J. Chem. Inf. Model. 52 (10): 2796–2806. doi:10.1021/ci300192.
  2. ^ "About". OpenHELM.org. Retrieved 14 Nov 2014.
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