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Alsever's solution

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Alsever's solution is a saline liquid used to prevent coagulation of human blood.[1][2] It is composed of an equal volume of 2% dextrose, 0.8% sodium citrate,0.5% citric acid, and 0.42% sodium chloride. This solution is used to study in vitro anti-inflammatory activity of crude drugs and in the HRBC (human red blood cell) stabilization method.[3] It is also used to preserve blood cells from other sources.[4][5]

References

  1. ^ Alsever, J. B., & Ainslie, R. B. (1941). A new method for the preparation of dilute blood plasma and the operation of a complete transfusion service. NY State J. Med, 41, 126-131.
  2. ^ Campbell, D. H. (1963). Methods in Immunology. A Laboratory Text for Instruction and Research. New York: W. A. Benjamin, Inc. p. 244. {{cite book}}: Unknown parameter |coauthors= ignored (|author= suggested) (help)
  3. ^ Gandhisan R, Thamaraichelvan A, Baburaj. Antiinflammatory action of Lannea coromandelica HRBC membrane stabilization. Fitotherapia 1991; 62: 82-83.
  4. ^ Schjerning-Thiesen, Knud (2009). "Experiments on the Stability of Sheep Erythrocytes Stored in Alsever's Solution". Acta Pathologica Microbiologica Scandinavica. 32: 198. doi:10.1111/j.1699-0463.1953.tb00242.x.
  5. ^ L.S.A., List of C.F.R. Sections Affected. 2003. p. 827.