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REM Sleep Behavior Disorder Screening Questionnaire

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Rapid Eye Movement sleep Behavior Disorder Screening Questionnaire (RBDSQ) is a specific questionnaire for RBD developed by Stiasny-Kolster and team [1], to assess the most prominent clinical features of RBD according to the International Classification on Sleep Disorders [2]. It is a 10-item, patient self-rating instrument with short questions to be answered by either 'yes' or 'no' [1]. The validity of the questionnaire was studied by researchers and they have observed it to perform with high sensitivity and reasonable specificity in the diagnosis of RBD [3][4][5] . Although the performance is good, for a definitive diagnosis polysomnography is required to definitely rule out differential diagnoses such as sleep-related epileptic seizures, non-REM parasomnias (e.g., sleepwalking), obstructive sleep apnea (OSA), or nocturnal periodic leg movements (PLM)[2].

RBDSQ has the potential to be useful as a screening instrument for neurodegenerative disorder, such as the α-synucleinopathies, Parkinson’s disease or multiple system atrophy which may enable early diagnosis and also recruitment of RBD patients necessary for research studies as well as for therapeutic trials.

References

  1. ^ a b Stiasny-Kolster, K (2007). "The REM Sleep Behavior Disorder Screening Questionnaire—A New Diagnostic Instrument". Movement Disorders. 22 (16): 2386–2393. PMID 17894337. {{cite journal}}: Unknown parameter |coauthors= ignored (|author= suggested) (help)
  2. ^ a b Atlas Task Force of the American Sleep Disorders Association (ASDA) (2005). "The International Classification of Sleep Disorders— Diagnostic and Coding Manual". Minnesota: Rochester.
  3. ^ Nomura, Takashi (August 2011). "Utility of the REM sleep behavior disorder screening questionnaire (RBDSQ) in Parkinson's disease patients". Sleep Medicine. 12 (7): 711–713. doi:10.1016/j.sleep.2011.01.015. PMID 21700495. {{cite journal}}: Unknown parameter |coauthors= ignored (|author= suggested) (help)
  4. ^ Miyamoto, Tomoyuki (December 2009). "The REM sleep behavior disorder screening questionnaire: Validation study of a Japanese version". Sleep Medicine. 10 (10): 1151–1154. doi:10.1016/j.sleep.2009.05.007. PMID 19604719. {{cite journal}}: Unknown parameter |coauthors= ignored (|author= suggested) (help)
  5. ^ Nihei, Yoshihiro (10 January 2012). "REM sleep behavior disorder in Japanese patients with Parkinson's disease: a multicenter study using the REM sleep behavior disorder screening questionnaire". Journal of Neurology. 259 (8): 1606–1612. doi:10.1007/s00415-011-6386-1. PMID 22231870. {{cite journal}}: Unknown parameter |coauthors= ignored (|author= suggested) (help)