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Poikiloderma

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Poikiloderma is a skin condition that consists of areas of increased and decreased pigmentation, prominent blood vessels, and thinning of the skin.[1]

Poikiloderma is most frequently seen on the chest or the neck, characterized by red colored pigment on the skin that is commonly associated with sun damage.

Health Risks

It is a condition that may present a cosmetic nuisance, yet it poses no health risks on its own.[2]

Pathogenesis

The exact cause of poikiloderma is unknown; however, extended sun exposure, namely the ultraviolet light emitted by the sun, is the primary factor.[3]

Causes

  • Congenital
  1. Rothmund-Thompson Syndrome
  2. Dyskeratosis Congenita
  3. Mendes da Costa Syndrome
  • Other Heriditary Causes
  1. Hereditary Sclerosing Poikiloderma of Weary
  2. Weary-Kindler Syndrome
  3. Kindler Syndrome
  4. Diffuse and Macular Atrophic Dermatosis
  5. Degos-Touraine Syndrome
  • Acquired
  1. Injury to cold, heat, ionizing radiation, exposure to sensitizing chemicals
  2. Lichen Planus
  3. Dermatomyositis
  4. Lupus Erythematosus
  5. Systemic Sclerosis
  6. Cutaneous T Cell Lymphomas

Treatment

Albeit difficult, treatment of poikiloderma involves the delivery of multiple wavelengths of intense pulsed light (IPL) to the affected area.[4]

Types include:

See also

References

  1. ^ Understanding Rothmund-Thomson Syndrome, Brochure produced by the RTS research group: Lisa L. Wang, MD, Moise L. Levy, MD, Richard A. Lewis, MD, Sharon E. Plon, MD, Ta-Tara Rideau.
  2. ^ Celibre Medical "Poikiloderma More Information", Celibre.com, referenced July 22, 2011.
  3. ^ American Osteopathic College of Dermatology "Dermatologic Disease Database", aocd.org, referenced July 22, 2011.
  4. ^ PubMed.gov "Treatment of poikiloderma of Civatte with an intense pulsed light source", PubMed.gov, referenced July 22, 2011.