Functional element SNPs database
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| Content | |
|---|---|
| Description | Functional Element SNPs Database in human. |
| Organisms | Homo sapiens |
| Contact | |
| Authors | Hyo Jin Kang |
| Primary citation | Kang & al. (2005)[1] |
| Access | |
| Website | http://combio.kribb.re.kr/ksnp/resd/ |
The Functional Element SNPs Database (FESD) is a biological database of SNPs in human Molecular biology.[1] The Functional Element SNPs Database (FESD) tool is designed to organize functional elements into categories in human gene regions and to output their sequences needed for genotyping experiments as well as provide a set of SNPs that lie within each region. The database defines functional elements into ten types: promoter regions, CpG islands,5' untranslated regions (5'-UTRs), translation start sites, splice sites, coding exons, introns, translation stop sites, polyadenylation signals, and 3' UTRs.[2][3] People may reference this database when haplotyping a gene or chromosome, in hopes of discovering mutations that cause disease. By utilizing the database, researchers can manually choose a group of SNPs of special interest for certain functional elements along with their corresponding sequences.[4] Also, FESD can be used to dteremine predisposition to diseases and conditions.[5] Although the database is useful, it relies on chromosome position and cytogenic banding patterns meaning it cannot recognize manually entered SNPs.[6][7]
References
- ^ a b . doi:10.1093/nar/gki082.
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{{cite journal}}: Cite journal requires|journal=(help); Missing or empty|title=(help) - ^ . doi:10.1142/S0219720007003090.
{{cite journal}}: Cite journal requires|journal=(help); Missing or empty|title=(help) - ^ . doi:10.1186/1471-2105-11-311.
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External links
- http://combio.kribb.re.kr/ksnp/resd/.
- . doi:10.1093/nar/gki082.
{{cite journal}}: Cite journal requires|journal=(help); Missing or empty|title=(help) - http://sysbio.kribb.re.kr:8080/fesd/
- . doi:10.1007/s10038-006-0102-5.
{{cite journal}}: Cite journal requires|journal=(help); Missing or empty|title=(help) - http://academic.research.microsoft.com/Paper/5643267
- http://www.ncbi.nlm.nih.gov/gene/3699