Small t intron

Small T intron exist in some plasmid vectors used for protein expression. The function of this intron in the vectors is unknown, but it is theorized that it might be involved in splicing or translation efficiency.^[1]^[2]

Vectors such as pME18s contain it.

References

^ Huang MT, Gorman CM (1990). "The simian virus 40 small-t intron, present in many common expression vectors, leads to aberrant splicing". Mol Cell Biol. 10 (4): 1805–10. PMC 362290. PMID 1690852.
^ Hunt AG, Mogen BD, Chu NM, Chua NH (1991). "The SV40 small t intron is accurately and efficiently spliced in tobacco cells". Plant Mol Biol. 16 (3): 375–9. PMID 1654158.{{cite journal}}: CS1 maint: multiple names: authors list (link)

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[pmid1690852-1] Huang MT, Gorman CM (1990). "The simian virus 40 small-t intron, present in many common expression vectors, leads to aberrant splicing". Mol Cell Biol. 10 (4): 1805–10. PMC 362290. PMID 1690852.

[pmid1654158-2] Hunt AG, Mogen BD, Chu NM, Chua NH (1991). "The SV40 small t intron is accurately and efficiently spliced in tobacco cells". Plant Mol Biol. 16 (3): 375–9. PMID 1654158.{{cite journal}}: CS1 maint: multiple names: authors list (link)

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