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Splicing regulatory element

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Splicing regulatory element (SRE) are trans-acting sequences in pre-mRNA, which either enhance or silence (suppress) the splicing of introns, or in general regulates the constitutive or alternative splicing.[1]

SREs are:

present in exons: exonic splicing enhancers (ESEs), exonic splicing silencers (ESSs)
present in introns: intronic splicing enhancers (ISEs), intronic splicing silencers (ISSs).

References

  1. ^ Wang, Zefeng (2008-05). "Splicing regulation: From a parts list of regulatory elements to an integrated splicing code". RNA. 14 (5): 802–813. doi:10.1261/rna.876308. ISSN 1355-8382. Retrieved 2013-08-15. {{cite journal}}: Check date values in: |date= (help); Unknown parameter |coauthors= ignored (|author= suggested) (help)
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