Slippery sequence
Appearance
Slippery sequence refers to a small section of condon sequences that controls the rate of ribosomal frameshifting. A slippery sequence resutls in a faster ribosomal transaction. Slippery sequences can potentially make the reading ribosome "slip" and allow a tRNA to shift by 1 base after it has paried with its anticodon, thereby changing the reading frame. [1]
See also
References
- ^ Green L, Kim CH, Bustamante C, Tinoco I Jr. "Characterization of the Mechanical Unfolding of RNA Pseudoknots." J Mol Biol. 26 May 2007