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Hepatitis E virus cis-reactive element

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Hepatitis E virus cis-reactive element
Predicted secondary structure and sequence conservation of HepE_CRE
Identifiers
SymbolHepE_CRE
RfamRF00550
Other data
RNA type Cis-reg
Domain(s)Viruses
SOSO:0000233
PDB structuresPDBe

The Hepatitis E virus cis-reactive element is a RNA element that is thought to be essential for "some step in gene expression".[1] The mutation of this element resulted in Hepatitis E strains which were unable to infect Rhesus macaques (Macaca mulatta).[1]

References

  1. ^ a b Graff, J (2005). "The open reading frame 3 gene of hepatitis E virus contains a cis-reactive element and encodes a protein required for infection of macaques". J Virol. 79 (11): 6680โ€“6689. doi:10.1128/JVI.79.11.6680-6689.2005. PMC 1112134. PMID 15890906. {{cite journal}}: Unknown parameter |coauthors= ignored (|author= suggested) (help)