Multisystem developmental disorder
Multisystem developmental disorder (MSDD) is a term used by Stanley Greenspan to describe children under age 3 who exhibit signs of impaired communication as in autism, but with strong emotional attachments atypical of autism.[citation needed] It is described in the DC:0-3R manual.[1]
Other uses of the term
The term multisystem developmental disorder has also been used to describe various developmental disorders. These include:
- Cornelia de Lange syndrome[2], an autosomal dominant disorder characterized by short stature, excessive hairiness, mental retardation, and problems with the sensory organs such as hearing loss, dry eyes, and lack of sensitivity to pain.[3]
- Alagille syndrome[4], an autosomal dominant disorder with a wide range of features and manifestations. Its five most significant features are chronic choleostasis, a condition where bile cannot flow from the liver to the duodenum, occurring in 95% of cases; heart abnormalities (over 90%); butterfly vertebrae; posterior embryotoxon and a distinctive face (prominent forehead, deep-set eyes, and a pointed chin)[5].
- Rubinstein-Taybi syndrome[6], a mental retardation syndrome characterized by broad thumbs, facial abnormalities, and big toes alongside mental retardation.[7]
- Renal-coloboma syndrome[8]
- Williams syndrome.[9][10], a neurodevelopmental disorder characterized by a unique profile of strengths and deficits; most with the condition have mild mental retardation but have grammatical and lexical abilities above what would be expected from their IQs.[11] They are hypersocial and empathetic, but social isolation is commonly experienced.[12]
- Proteus syndrome[13], a congenital disorder causing disproportionate growth of skin, bone, and other tissues.[14]
- Asphyxiating thoracic dysplasia[15], a autosomal recessive skeletal disorder with an estimated prevalence of between 1 in 100,000 and 1 in 130,000 live births[16] .
Symptoms
- Toe walking[17]
- Pragmatic speech problems[18]
- Clumsiness[19]
- Obsessions and rituals[20]
- Sensory issues[21]
- Disinterest in social interaction[22]
- Autistic characteristics[23]
References
- ^ "Developmentally-Sensitive Diagnostic Criteria for Mental Health Disorders in Early Childhood: DSM-IV, RDC-PA, and the revised DC: 0-3". 2011.
{{cite journal}}: Cite journal requires|journal=(help); Unknown parameter|month=ignored (help) - ^ Attention: This template ({{cite pmid}}) is deprecated. To cite the publication identified by PMID 19019222, please use {{cite journal}} with
|pmid=19019222instead. - ^ Woliver, Robbie. Alphabet Kids. pp. 160, 161.
- ^ Attention: This template ({{cite pmid}}) is deprecated. To cite the publication identified by PMID 12244552, please use {{cite journal}} with
|pmid=12244552instead. - ^ Turnpenny, Peter (2011). "Alagille syndrome: pathogenesis, diagnosis and management". European Journal of Human Genetics.
{{cite journal}}: Unknown parameter|coauthors=ignored (|author=suggested) (help) - ^ Attention: This template ({{cite pmid}}) is deprecated. To cite the publication identified by PMID 8726717, please use {{cite journal}} with
|pmid=8726717instead. - ^ "Urology".
{{cite journal}}: Cite journal requires|journal=(help) - ^ "Renal-coloboma syndrome: a multi-system developmental disorder caused by PAX2 mutations". Clinical Genetics. 56. 1999.
{{cite journal}}: Unknown parameter|month=ignored (help) - ^ Attention: This template ({{cite pmid}}) is deprecated. To cite the publication identified by PMID 9761391, please use {{cite journal}} with
|pmid=9761391instead. - ^ Attention: This template ({{cite pmid}}) is deprecated. To cite the publication identified by PMID 17009066, please use {{cite journal}} with
|pmid=17009066instead. - ^ http://www.wschanginglives.org/uploads/An_Unusual_Neuropsychological_Profile.pdf.
{{cite journal}}: Cite journal requires|journal=(help); Missing or empty|title=(help) - ^ Williams-Beuren Syndrome: Research, Evaluation, and Treatment. p. 237.
- ^ "Imaging manifestations in Proteus syndrome: an unusual multisystem developmental disorder". 18.
{{cite journal}}: Check date values in:|date=and|year=/|date=mismatch (help); Cite journal requires|journal=(help); Unknown parameter|month=ignored (help) - ^ "Assessment and management of the orthopedic and other complications of Proteus syndrome".
{{cite journal}}: Cite journal requires|journal=(help) - ^ "A locus for asphyxiating thoracic dystrophy, ATD, maps to chromosome 15q13". 40 (6). 2003. Retrieved 24/04/2013.
{{cite journal}}: Check date values in:|accessdate=(help); Cite journal requires|journal=(help); Unknown parameter|month=ignored (help) - ^ http://cat.inist.fr/?aModele=afficheN&cpsidt=1993559.
{{cite journal}}: Cite journal requires|journal=(help); Missing or empty|title=(help) - ^ Woliver, Robbie (2009). Alphabet Kids. Jessica Kingsley Publishers. p. 295.
- ^ Woliver, Robbie (2009). Alphabet Kids. Jessica Kingsley Publishers. p. 295.
- ^ Woliver, Robbie (2009). Alphabet Kids. Jessica Kingsley Publishers. p. 295.
- ^ Woliver, Robbie (2009). Alphabet Kids. Jessica Kingsley Publishers. p. 295.
- ^ Woliver, Robbie (2009). Alphabet Kids. Jessica Kingsley Publishers. p. 295.
- ^ Woliver, Robbie (2009). Alphabet Kids. Jessica Kingsley Publishers. p. 295.
- ^ Woliver, Robbie (2009). Alphabet Kids. Jessica Kingsley Publishers. p. 295.
Sources
PubMed
- Attention: This template ({{cite pmid}}) is deprecated. To cite the publication identified by PMID 11579660, please use {{cite journal}} with
|pmid=11579660instead.
Other sources
- Multisystem Developmental Disorder, Developmental Behavior Pediatrics Online
- Increasing Interaction with Children with Multisystem Developmental Disorder (MSDD), Developmental Delay Resources
- Integrated Treatment Approaches for Young Children with Multisystem Developmental Disorder, Education Resources Information Center
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