Jump to content

Multisystem developmental disorder

From Wikipedia, the free encyclopedia
This is an old revision of this page, as edited by Shiningroad (talk | contribs) at 05:30, 24 April 2013 (Other uses of the term). The present address (URL) is a permanent link to this revision, which may differ significantly from the current revision.

Multisystem developmental disorder (MSDD) is a term used by Stanley Greenspan to describe children under age 3 who exhibit signs of impaired communication as in autism, but with strong emotional attachments atypical of autism.[citation needed] It is described in the DC:0-3R manual.[1]

Other uses of the term

The term multisystem developmental disorder has also been used to describe various developmental disorders. These include:

  • Cornelia de Lange syndrome[2], an autosomal dominant disorder characterized by short stature, excessive hairiness, mental retardation, and problems with the sensory organs such as hearing loss, dry eyes, and lack of sensitivity to pain.[3]
  • Alagille syndrome[4], an autosomal dominant disorder with a wide range of features and manifestations. Its five most significant features are chronic choleostasis, a condition where bile cannot flow from the liver to the duodenum, occurring in 95% of cases; heart abnormalities (over 90%); butterfly vertebrae; posterior embryotoxon and a distinctive face (prominent forehead, deep-set eyes, and a pointed chin)[5].
  • Rubinstein-Taybi syndrome[6], a mental retardation syndrome characterized by broad thumbs, facial abnormalities, and big toes alongside mental retardation.[7]
  • Renal-coloboma syndrome[8]
  • Williams syndrome.[9][10], a neurodevelopmental disorder characterized by a unique profile of strengths and deficits; most with the condition have mild mental retardation but have grammatical and lexical abilities above what would be expected from their IQs.[11] They are hypersocial and empathetic, but social isolation is commonly experienced.[12]
  • Proteus syndrome[13], a congenital disorder causing disproportionate growth of skin, bone, and other tissues.[14]
  • Asphyxiating thoracic dysplasia[15], a autosomal recessive skeletal disorder with an estimated prevalence of between 1 in 100,000 and 1 in 130,000 live births[16] .

Symptoms

  • Toe walking[17]
  • Pragmatic speech problems[18]
  • Clumsiness[19]
  • Obsessions and rituals[20]
  • Sensory issues[21]
  • Disinterest in social interaction[22]
  • Autistic characteristics[23]

References

  1. ^ "Developmentally-Sensitive Diagnostic Criteria for Mental Health Disorders in Early Childhood: DSM-IV, RDC-PA, and the revised DC: 0-3". 2011. {{cite journal}}: Cite journal requires |journal= (help); Unknown parameter |month= ignored (help)
  2. ^ Attention: This template ({{cite pmid}}) is deprecated. To cite the publication identified by PMID 19019222, please use {{cite journal}} with |pmid=19019222 instead.
  3. ^ Woliver, Robbie. Alphabet Kids. pp. 160, 161.
  4. ^ Attention: This template ({{cite pmid}}) is deprecated. To cite the publication identified by PMID 12244552, please use {{cite journal}} with |pmid=12244552 instead.
  5. ^ Turnpenny, Peter (2011). "Alagille syndrome: pathogenesis, diagnosis and management". European Journal of Human Genetics. {{cite journal}}: Unknown parameter |coauthors= ignored (|author= suggested) (help)
  6. ^ Attention: This template ({{cite pmid}}) is deprecated. To cite the publication identified by PMID 8726717, please use {{cite journal}} with |pmid=8726717 instead.
  7. ^ "Urology". {{cite journal}}: Cite journal requires |journal= (help)
  8. ^ "Renal-coloboma syndrome: a multi-system developmental disorder caused by PAX2 mutations". Clinical Genetics. 56. 1999. {{cite journal}}: Unknown parameter |month= ignored (help)
  9. ^ Attention: This template ({{cite pmid}}) is deprecated. To cite the publication identified by PMID 9761391, please use {{cite journal}} with |pmid=9761391 instead.
  10. ^ Attention: This template ({{cite pmid}}) is deprecated. To cite the publication identified by PMID 17009066, please use {{cite journal}} with |pmid=17009066 instead.
  11. ^ http://www.wschanginglives.org/uploads/An_Unusual_Neuropsychological_Profile.pdf. {{cite journal}}: Cite journal requires |journal= (help); Missing or empty |title= (help)
  12. ^ Williams-Beuren Syndrome: Research, Evaluation, and Treatment. p. 237.
  13. ^ "Imaging manifestations in Proteus syndrome: an unusual multisystem developmental disorder". 18. {{cite journal}}: Check date values in: |date= and |year= / |date= mismatch (help); Cite journal requires |journal= (help); Unknown parameter |month= ignored (help)
  14. ^ "Assessment and management of the orthopedic and other complications of Proteus syndrome". {{cite journal}}: Cite journal requires |journal= (help)
  15. ^ "A locus for asphyxiating thoracic dystrophy, ATD, maps to chromosome 15q13". 40 (6). 2003. Retrieved 24/04/2013. {{cite journal}}: Check date values in: |accessdate= (help); Cite journal requires |journal= (help); Unknown parameter |month= ignored (help)
  16. ^ http://cat.inist.fr/?aModele=afficheN&cpsidt=1993559. {{cite journal}}: Cite journal requires |journal= (help); Missing or empty |title= (help)
  17. ^ Woliver, Robbie (2009). Alphabet Kids. Jessica Kingsley Publishers. p. 295.
  18. ^ Woliver, Robbie (2009). Alphabet Kids. Jessica Kingsley Publishers. p. 295.
  19. ^ Woliver, Robbie (2009). Alphabet Kids. Jessica Kingsley Publishers. p. 295.
  20. ^ Woliver, Robbie (2009). Alphabet Kids. Jessica Kingsley Publishers. p. 295.
  21. ^ Woliver, Robbie (2009). Alphabet Kids. Jessica Kingsley Publishers. p. 295.
  22. ^ Woliver, Robbie (2009). Alphabet Kids. Jessica Kingsley Publishers. p. 295.
  23. ^ Woliver, Robbie (2009). Alphabet Kids. Jessica Kingsley Publishers. p. 295.

Sources

PubMed

  • Attention: This template ({{cite pmid}}) is deprecated. To cite the publication identified by PMID 11579660, please use {{cite journal}} with |pmid=11579660 instead.

Other sources