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Analysis of molecular variance

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Analysis of molecular variance (AMOVA), is a statistical model for the molecular variation in a single species, typically biological.[1] The name and model are inspired by ANOVA. The method was developed by Laurent Excoffier, Peter Smouse and Joseph Quattro at Rutgers University in 1992.

Since developing AMOVA, Excoffier has written a program for running such analyses. This program, which runs on Windows is called Arlequin, and is freely available on Excoffier's website. There is also an implementation by Sandrine Pavoine in R language in the ade4 package available on CRAN (Comprehensive R Archive Network). Another implementation is in Info-Gen, which also runs on Windows. The student version is free and fully functional. Native language of the application is Spanish but an English version is also available.

References

  1. ^ Excoffier, L; Smouse, Pe; Quattro, Jm (1992). "Analysis of molecular variance inferred from metric distances among DNA haplotypes: application to human mitochondrial DNA restriction data" (Free full text). Genetics. 131 (2): 479–91. ISSN 0016-6731. PMC 1205020. PMID 1644282. {{cite journal}}: Unknown parameter |month= ignored (help)CS1 maint: multiple names: authors list (link)