Digital transcriptome subtraction

Digital transcriptome subtraction, or DTS, is a bioinformatic method developed by Feng et al^[1] to detectnon-human transcripts by eliminating in silico the known-human transcripts. The method is best known for discover Merkel cell polymavirus, the suspect causative agent in Merkel cell carcinoma.

References

^ Feng, Huichen (8). "Human Transcriptome Subtraction by Using Short Sequence Tags To Search for Tumor Viruses in Conjunctival Carcinoma". Journal of Virology. 20. 81: 11332–11340. doi:doi:10.1128/JVI.00875-07. PMID 17686852. {{cite journal}}: Check |doi= value (help); Check date values in: |date= and |year= / |date= mismatch (help); Unknown parameter |coauthors= ignored (|author= suggested) (help); Unknown parameter |month= ignored (help)

[1] Feng, Huichen (8). "Human Transcriptome Subtraction by Using Short Sequence Tags To Search for Tumor Viruses in Conjunctival Carcinoma". Journal of Virology. 20. 81: 11332–11340. doi:doi:10.1128/JVI.00875-07. PMID 17686852. {{cite journal}}: Check |doi= value (help); Check date values in: |date= and |year= / |date= mismatch (help); Unknown parameter |coauthors= ignored (|author= suggested) (help); Unknown parameter |month= ignored (help)

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