Critical Assessment of Function Annotation

The Critical Assessment of protein Function Annotation algorithms (CAFA) is an experiment designed to provide a large-scale assessment of computational methods dedicated to predicting protein function. Different algorithms are evaluated by their ability to predict the Gene Ontology (GO) terms in the categories of Molecular Function and Biological Process. The experiment consists of two tracks: (i) the eukaryotic track, (ii) the prokaryotic track. In each track, a set of targets is provided by the organizers. Participants are expected to submit their predictions by the submission deadline, after which they are assessed according to a set of specific metrics.