Barrier to autointegration factor 1

Template:PBB Barrier-to-autointegration factor is a protein that in humans is encoded by the BANF1 gene.^[1]^[2] It is a member of the barrier-to-autointegration factor family of proteins.

Template:PBB Summary It also associates with the LEM Domain containing proteins LAP2, Emerin, and MAN1.

Interactions

Barrier to autointegration factor 1 has been shown to interact with Thymopoietin.^[3]

Mutations in this gene have been shown to cause hereditary progeroid syndrome.^[4]

^ Lee MS, Craigie R (1998). "A previously unidentified host protein protects retroviral DNA from autointegration". Proc Natl Acad Sci U S A. 95 (4): 1528–33. doi:10.1073/pnas.95.4.1528. PMC 19075. PMID 9465049. {{cite journal}}: Unknown parameter |month= ignored (help)
^ "Entrez Gene: BANF1 barrier to autointegration factor 1".
^ Furukawa, K (1999). "LAP2 binding protein 1 (L2BP1/BAF) is a candidate mediator of LAP2-chromatin interaction". J. Cell. Sci. 112 ( Pt 15). ENGLAND: 2485–92. ISSN 0021-9533. PMID 10393804. {{cite journal}}: Check date values in: |year= (help); Cite has empty unknown parameters: |laysummary=, |laydate=, and |laysource= (help); Unknown parameter |month= ignored (help)CS1 maint: year (link)
^ Puente XS, Quesada V, Osorio FG, Cabanillas R, Cadiñanos J, Fraile JM, Ordóñez GR, Puente DA, Gutiérrez-Fernández A, Fanjul-Fernández M, Lévy N, Freije JM, López-Otín C (2011). "Exome sequencing and functional analysis identifies BANF1 mutation as the cause of a hereditary progeroid syndrome". Am. J. Hum. Genet. 88 (5): 650–6. doi:10.1016/j.ajhg.2011.04.010. PMC 3146734. PMID 21549337. {{cite journal}}: Unknown parameter |month= ignored (help)CS1 maint: multiple names: authors list (link)