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Virus Pathogen Database and Analysis Resource

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Virus Pathogen Database and Analysis Resource (ViPR) is a publicly available one-stop database and analysis resource to search, analyze, visualize, save and share data for viral pathogens in the U.S. National Institutes of Allergy and Infectious Diseases (NIAID) Category A-C Priority Pathogen lists for biodefense research, and other viral pathogens causing emerging/reemerging infectious diseases. ViPR is one of the five Bioinformatics Resource Centers (BRC) funded by NIAID, a component of the National Institutes of Health (NIH), which is an agency of the United States Department of Health and Human Services.

Virus families covered in ViPR

  • Arenaviridae
  • Bunyaviridae
  • Caliciviridae
  • Coronaviridae
  • Filoviridae
  • Flaviviridae
  • Hepeviridae
  • Herpesviridae
  • Paramyxoviridae
  • Picornaviridae
  • Poxviridae
  • Reoviridae
  • Rhabdoviridae
  • Togaviridae

Data types in ViPR

  • Genomes
  • Genome annotations
  • Genes & proteins
  • Immune epitopes
  • Sequence Features
  • 3D protein structures
  • Clinical and surveillance data
  • Computationally-derived data
  • Host-pathogen interactions (coming soon)

Analysis and visualization tools in ViPR

  • BLAST sequence similarity search
  • Multiple sequence alignment
  • Phylogenetic tree construction
  • 3D protein structures with Sequence Feature or epitope highlights
  • Sequence Feature Variant Type (SFVT) analysis
  • Metadata-driven comparative analysis
  • SNP analysis
  • Genome annotation
  • Personal Workbench to save and share data and analysis