RefSeq
 | |
| Content | |
|---|---|
| Description | curated non-redundant sequence database of genomes. |
| Contact | |
| Research center | National Center for Biotechnology Information |
| Primary citation | Pruitt KD & al. (2005)[1] |
| Access | |
| Website | http://www.ncbi.nlm.nih.gov/RefSeq |
The Reference Sequence (RefSeq) database[1] is an open access, annotated and curated collection of publicly available nucleotide sequences (DNA, RNA) and their protein products. This database is built by National Center for Biotechnology Information (NCBI), and, unlike GenBank, provides only single record for each natural biological molecule(i.e. DNA, RNA or protein) for major organisms ranging from viruses to bacteria to eukaryotes.
For each model organism, RefSeq aims to provide separate and linked records for the genomic DNA, the gene transcripts, and the proteins arising from those transcripts. RefSeq is limited to major organisms for which sufficient data is available (more than 16,000 distinct “named” organisms as of September 2011),[2] while GenBank includes sequences for any organism submitted (approximately 250,000 different named organisms).
RefSeq categories
| Category | Description |
|---|---|
| NC | Complete genomic molecules |
| NG | Incomplete genomic region |
| NM | mRNA |
| NR | ncRNA |
| NP | Protein |
| XM | mRNA of under curation process |
| XP | Protein of under curation process |
References
- ^ a b Pruitt KD, Tatusova T, Maglott DR (2005). "NCBI Reference Sequence (RefSeq): a curated non-redundant sequence database of genomes, transcripts and proteins". Nucleic Acids Res. 33 (Database issue): D501-4. doi:10.1093/nar/gki025. PMC 539979. PMID 15608248.
{{cite journal}}: CS1 maint: multiple names: authors list (link) - ^ RefSeq Release 49 Statistics (Report). National Library of Medicine. 2011. Retrieved 20 September 2011.
See also
- GenBank
- Sequence analysis
- Sequence profiling tool
- Sequence motif
- UniProt
- List of sequenced eukaryotic genomes
- List of sequenced archeal genomes
External links
- mybioinfo.info get a RefSeq list for your genes of interest (mRNA and protein).
- RefSeq
- GenBank, RefSeq, TPA and UniProt: What’s in a Name?
Sources
This article incorporates public domain material from NCBI Handbook. National Center for Biotechnology Information.