Replicative transposition

Replicative transposition is a mechanism of transposition in molecular biology, proposed by James A. Shapiro in 1979,^[1] in which the transposable element is duplicated during the reaction, so that the transposing entity is a copy of the original element. In this mechanism, the donor and receptor DNA sequences form a characteristic intermediate "theta" configuration.^[2] Replicative transposition is characteristic to retrotransposons and occurs from time to time in class II transposons.^{[citation needed]}

References

^ Shapiro, J. A. (1979), "Molecular model for the transposition and replication of bacteriophage Mu and other transposable elements" (PDF), Proceedings of the National Academy of Sciences of the United States of America, 76: 1933–1937, PMID 287033.
^ Bushman, Frederic (2002), Lateral DNA transfer: mechanisms and consequences, CSHL Press, p. 46, ISBN 9780879696214.

[1] Shapiro, J. A. (1979), "Molecular model for the transposition and replication of bacteriophage Mu and other transposable elements" (PDF), Proceedings of the National Academy of Sciences of the United States of America, 76: 1933–1937, PMID 287033.

[2] Bushman, Frederic (2002), Lateral DNA transfer: mechanisms and consequences, CSHL Press, p. 46, ISBN 9780879696214.

[1]

[2]