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Subfunctionalization

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Subfunctionalization is a model that explains the process by which duplicated genes remain functional in a genome. Duplicated genes are frequently formed in eukaryotic genomes and are thought to be initially redundant in function. One of the extra copies is usually under relaxed selection and therefore acquires degenerative mutations that render it nonfunctional. To explain the high percentage of duplicated genes in eukaryotic genomes several theories have been proposed, such as subfunctionalization [1]. The DDC(Duplication-degenaration-complementation) subfunctionalization model was proposed by Force et al.Cite error: A <ref> tag is missing the closing </ref> (see the help page).

See also

References

  1. ^ Allan Force, Michael Lynch, F. Bryan Pickett, Angel Amores, Yi-lin Yan & John Postlethwait (1999). "Preservation of duplicate genes by complementary, degenerative mutations". Genetics. 151 (4): 1531–1545. PMID 10101175.{{cite journal}}: CS1 maint: multiple names: authors list (link)


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