Monooxygenase DBH-like 1
Template:PBB MOXD1 monooxygenase, DBH-like 1 . DBH-like 1 maintains many of the structural features of dopamine beta-monooxygenase DBH.[1] Since Peptidylglycine alpha-hydroxylating monooxygenase (PHM; EC 1.14.17.3) is homologous to dopamine beta-monooxygenase (DBM; EC 1.14.17.1)[2] this concerns a structural basis for a new family of copper type II, signficantly specific for ascorbate-dependent monooxygenases[2] based on the corresponding mouse homolog.[3] The pathway of catecholamine synthesis is a possible catecholamine-binding metabolic copper[4] enzyme domain, a neuron-like property encoding MOX without a signal sequence enzyme metabolism resolving the monooxygenase X chemical pathway[4] of an unknown substrate[3], exogenous MOX is not secreted, and it localizes throughout the endoplasmic reticulum[4], in both endocrine or nonendocrine cells.[4]
Interactions
See Also
moxd1 moxd1l monooxygenase, DBH-like 1, like.[4][5]
References
- ^ Prigge ST, Mains RE, Eipper BA, Amzel LM.. (2000). "New insights into copper monooxygenases and peptide amidation: structure, mechanism and function". Cell Mol Life Sci. 57 (8–9): 1236–59. doi:10.1007/PL00000763. ISSN 1420-682X. PMID 11028916.
{{cite journal}}: Unknown parameter|month=ignored (help)CS1 maint: multiple names: authors list (link) - ^ a b Southan C, Kruse LI.. (1989). "Sequence similarity between dopamine beta-hydroxylase and peptide alpha-amidating enzyme: evidence for a conserved catalytic domain". FEBS Lett. 255 (1): 116–20. doi:10.1016/0014-5793(89)81072-5. PMID 2792366.
{{cite journal}}: Unknown parameter|month=ignored (help) - ^ a b Chambers KJ, Tonkin LA, Chang E, Shelton DN, Linskens MH, Funk WD. (1998). "Identification and cloning of a sequence homologue of dopamine beta-hydroxylase". Gene. 218 (1–2): 110–20. ISSN 0378-1119. PMID 9751809.
{{cite journal}}: Unknown parameter|month=ignored (help)CS1 maint: multiple names: authors list (link) - ^ a b c d e Xin X, Mains RE, Eipper BA.. (2004). "Monooxygenase X, a member of the copper-dependent monooxygenase family localized to the endoplasmic reticulum". J. Biol. Chem. 279 (46): 48159–67. doi:10.1074/jbc.M407486200. PMID 15337741.
{{cite journal}}: Unknown parameter|month=ignored (help)CS1 maint: multiple names: authors list (link) CS1 maint: unflagged free DOI (link) Cite error: The named reference "pmid15337741" was defined multiple times with different content (see the help page). - ^ Clark HF, Gurney AL, Abaya E; et al. (2003). "The secreted protein discovery initiative (SPDI), a large-scale effort to identify novel human secreted and transmembrane proteins: a bioinformatics assessment". Genome Res. 13 (10): 2265–70. doi:10.1101/gr.1293003. PMID 12975309.
{{cite journal}}: Explicit use of et al. in:|author=(help)CS1 maint: multiple names: authors list (link)
Further reading
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