Terminal complement pathway deficiency
| Terminal complement pathway deficiency |
|---|
Terminal complement pathway deficiency is a genetic condition affecting the complement membrane attack complex (MAC).
It involves deficiencies of C5, C6, C7, and C8. (While C9 is part of the MAC, it is not required for cell lysis.)[1]
People with this condition are prone to meningococcal infection.[2] Vaccination may be recommended.[3]
References
- ^ Thomas M. Habermann; Mayo Clinic (1 November 2007). Mayo Clinic Internal Medicine Concise Textbook. CRC Press. pp. 30–. ISBN 9781420067491. Retrieved 14 November 2010.
- ^ J.K. Sinha & S. Bhattacharya. A Text Book of Immunology. Academic Publishers. pp. 385–. ISBN 9788189781095. Retrieved 14 November 2010.
- ^ Frederick S. Southwick (10 December 2007). Infectious diseases: a clinical short course. McGraw Hill Professional. pp. 149–. ISBN 9780071477222. Retrieved 14 November 2010.
 | This medical article is a stub. You can help Wikipedia by expanding it. |