PyBOP

PyBOP
Names
	IUPAC name (Benzotriazol-1-yloxy)tripyrrolidinophosphonium hexafluorophosphate
	Other names PyBOP
Identifiers
CAS Number	128625-52-5;
3D model (JSmol)	Interactive image;
ChemSpider	2006820;
ECHA InfoCard	100.125.168
PubChem CID	2724699;
CompTox Dashboard (EPA)	DTXSID40369209 ;
	InChI InChI=1/C18H28N6OP.F6P/c1-2-10-18-17(9-1)19-20-24(18)25-26(21-11-3-4-12-21,22-13-5-6-14-22)23-15-7-8-16-23;1-7(2,3,4,5)6/h1-2,9-10H,3-8,11-16H2;/q+1;-1 Key: VIAFLMPQBHAMLI-UHFFFAOYAY;
	SMILES F[P-](F)(F)(F)(F)F.n4nn(O[P+](N1CCCC1)(N2CCCC2)N3CCCC3)c5ccccc45;
Properties
Chemical formula	C18H28N6OP·PF6
Molar mass	520.39 g/mol
Appearance	White crystals
Melting point	150 °C
Hazards
	Occupational safety and health (OHS/OSH):
Main hazards	Irritant
	Except where otherwise noted, data are given for materials in their standard state (at 25 °C [77 °F], 100 kPa). Infobox references

PyBOP is the common name for the chemical benzotriazol-1-yl-oxytripyrrolidinophosphonium hexafluorophosphate, a peptide coupling reagent used in solid phase peptide synthesis. It is used as a substitute for the BOP reagent, thus avoiding the formation of the carcinogenic side product HMPA.

See also