PyBOP
Appearance
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Names | |
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IUPAC name
(Benzotriazol-1-yloxy)tripyrrolidinophosphonium hexafluorophosphate
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Other names
PyBOP
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Identifiers | |
3D model (JSmol)
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ECHA InfoCard | 100.125.168 |
CompTox Dashboard (EPA)
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Properties | |
C18H28N6OP·PF6 | |
Molar mass | 520.39 g/mol |
Appearance | White crystals |
Melting point | 150 °C |
Hazards | |
Occupational safety and health (OHS/OSH): | |
Main hazards
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Irritant |
Except where otherwise noted, data are given for materials in their standard state (at 25 °C [77 °F], 100 kPa).
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PyBOP is the common name for the chemical benzotriazol-1-yl-oxytripyrrolidinophosphonium hexafluorophosphate, a peptide coupling reagent used in solid phase peptide synthesis. It is used as a substitute for the BOP reagent, thus avoiding the formation of the carcinogenic side product HMPA.
See also
- BOP reagent (Benzotriazole-1-yl-oxy-tris-(dimethylamino)-phosphonium hexafluorophosphate)