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Pyruvate dehydrogenase (NADP+)

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Pyruvate dehydrogenase (NADP⁺) EC 1.2.1.51 is an enzyme that should not be confused with Pyruvate dehydrogenase (acetyltransferase) EC 1.2.4.1.

It catalyzes the following reaction:

Pyruvate + Coenzyme A + NADP⁺ ⇒ acetyl-CoA + NADPH + H⁺ + CO₂

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