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Inclusive composite interval mapping

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In the last twenty years, rapid increase in the availability of fine-scale genetic marker maps makes possible the dissection of single quantitative trait gene. Based on genetic linkage map and phenotypic data, QTL (quantitative trait locus) mapping [[1]] was proposed to locate individual genetic factors on chromosomes and estimate their genetic effects. Composite interval mapping (CIM), proposed by Zeng (1994), is one of the most commonly used methods for mapping QTL with populations derived from bi-parental crosses. Inclusive composite interval mapping (ICIM) was proposed by Dr. Jiankang Wang’s group [[2]] to deal with the problems of CIM while retaining other advantages related to CIM. The details of ICIM are described below.

Background