Lattice model
Lattice model may refer to:
- Lattice model (physics), a physical model that is defined on a periodic structure with a repeating elemental unit pattern, as opposed to the continuum of space or spacetime
- Lattice model (finance)
- Lattice model (mathematics) A lattice (model) may be viewed as a regular tiling of a space by a primitive cell.
- In computational biology, lattice models are formulated with the help of Markov chains and usually referred to as Hidden Markov Models.
- In biophysics, one-dimensional lattice models are widely used for the description of biological polymers, such DNA and actin, while two-dimensional lattice models are used for protein binding to the lipid membrane. The general concept is to divide the system into the elementary units that are associated with different states (e.g. bound/unbound). The states of the whole system are then calculated as different combinations of states of elementary units. The elementary DNA units are usually taken as nucleotides A, T, C and G. Other choices of the elementary lattice unit are also possible. Several methods of constructing lattice models of DNA-protein binding have been developed in the past. They may be roughly divided into four classes: combinatorial methods, generating functions, recurrent relations and the transfer-matrix method.[1]
References
- ^ Teif V.B. (2007). "General transfer matrix formalism to calculate DNA–protein–drug binding in gene regulation". Nucleic Acids Res. 35 (e80). doi:10.1093/nar/gkm268.
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