Afterhyperpolarization

Afterhyperpolarization describes the part of the hyperpolarization phase of an action potential where the membrane falls below the normal resting potential. Both medium and slow afterhyperpolarization currents (mI_AHP and sI_AHP, respectively) can be demonstrated in neurons.^[1] The SK channel is the major mediator of afterhyperpolarization currents, although other candidate mediators have been suggested.

References

^ M. Shah, and D. G. Haylett. Ca2+ Channels Involved in the Generation of the Slow Afterhyperpolarization in Cultured Rat Hippocampal Pyramidal Neurons. J Neurophysiol 83: 2554-2561, 2000.

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[1] M. Shah, and D. G. Haylett. Ca2+ Channels Involved in the Generation of the Slow Afterhyperpolarization in Cultured Rat Hippocampal Pyramidal Neurons. J Neurophysiol 83: 2554-2561, 2000.

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